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Omega Fund Management, LLC

Q1 2026 · 13F-HR

Omega Fund Management, LLCholdings as filed

Filed 2026-05-15 · accession 0001193125-26-225480

$163.1M
Reported value
10
Positions
2026-03-31
Period end
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The Brief · Omega Fund Management, LLC · Q1 2026

AI · grounded in 13F

Omega Fund Management, LLC closed its entire position in Upstream Bio Inc. UPB, reducing its exposure by $36.0M. The fund also trimmed its holdings in Alumis Inc. ALMS by 63.1% and Kestra Med Technologies Ltd KMTS by 25.6%. Conversely, the manager accumulated more shares of Bicara Therapeutics Inc. BCAX, increasing the position by 8.5%.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
055477103BCAXBicara Therapeutics Inc.$47.6M29.2%2,392,150CommonSOLE
67080N101NUVBNuvation Bio Inc.$34.7M21.2%8,081,089CommonSOLE
107924102BBOTBridgeBio Oncology Therapeutics Inc.$29.4M18.0%3,289,661CommonSOLE
G52441105KMTSKestra Med Technologies Ltd$20.4M12.5%1,022,149CommonSOLE
08659B102BBNXBeta Bionics Inc.$13.2M8.08%1,316,183CommonSOLE
29286M105enGene Holdings Inc.$6.0M3.66%876,357CommonSOLE
022307102ALMSAlumis Inc.$5.3M3.26%241,255CommonSOLE
799566104SANASana Biotechnology, Inc.$2.4M1.49%843,750CommonSOLE
45175G207IMAImageneBio, Inc.$2.3M1.40%455,361CommonSOLE
76029N106REPLReplimune Group$1.9M1.17%248,672CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.