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Commodore Capital LP

Q3 2025 · 13F-HR

Commodore Capital LPholdings as filed

Filed 2025-11-14 · accession 0001831942-25-000023

$2.05B
Reported value
37
Positions
2025-09-30
Period end
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The Brief · Commodore Capital LP · Q3 2025

AI · grounded in 13F

Commodore Capital LP closed its position in Scholar Rock Hldg Corp SRRK, reducing exposure by $51.36M. The fund established new positions in Amylyx Pharmaceuticals Inc AMLX for $55.39M and Terns Pharmaceuticals Inc 430 for $42.81M. Additionally, the fund increased its holdings in Cogent Biosciences Inc COGT by 213.69% and Soleno Therapeutics Inc SLNO by 121.31%.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
N5749R1002GHMERUS N V$331.9M16.2%3,525,000CommonSOLE
670703107NUVLNUVALENT INC$121.1M5.91%1,400,000CommonSOLE
98420N105XENEXENON PHARMACEUTICALS INC$108.4M5.29%2,700,000CommonSOLE
19240Q201COGTCOGENT BIOSCIENCES INC$104.1M5.08%7,250,000CommonSOLE
29337E102ELVNENLIVEN THERAPEUTICS INC$96.1M4.69%4,692,809CommonSOLE
00847X104AGIOAGIOS PHARMACEUTICALS INC$93.9M4.58%2,338,287CommonSOLE
G01767105ALKSALKERMES PLC$92.9M4.54%3,096,754CommonSOLE
834203309SLNOSOLENO THERAPEUTICS INC$91.3M4.46%1,350,000CommonSOLE
75943R102RLAYRELAY THERAPEUTICS INC$88.7M4.33%17,000,000CommonSOLE
15117B202CLDXCELLDEX THERAPEUTICS INC NEW$78.3M3.82%3,028,335CommonSOLE
152309100CNTACENTESSA PHARMACEUTICALS PLC$69.1M3.37%2,850,000CommonSOLE
92790C104VRDNVIRIDIAN THERAPEUTICS INC$69.1M3.37%3,200,000CommonSOLE
74366E102PTGXPROTAGONIST THERAPEUTICS INC$68.1M3.32%1,025,000CommonSOLE
N69605108PHVSPHARVARIS N V$60.3M2.95%2,418,476CommonSOLE
171757206CDTXCIDARA THERAPEUTICS INC$56.0M2.73%585,000CommonSOLE
03237H101AMLXAMYLYX PHARMACEUTICALS INC$55.4M2.70%4,075,478CommonSOLE
90240B106TYRATYRA BIOSCIENCES INC$47.2M2.30%3,375,000CommonSOLE
880881107430TERNS PHARMACEUTICALS INC$42.8M2.09%5,700,000CommonSOLE
501575104KYMRKYMERA THERAPEUTICS INC$42.5M2.07%750,000CommonSOLE
60255C885BRD1EURMIND MEDICINE MINDMED INC$38.0M1.86%3,225,000CommonSOLE
67080M103NRIXNURIX THERAPEUTICS INC$34.9M1.71%3,780,055CommonSOLE
687604108ORKAORUKA THERAPEUTICS INC$33.7M1.65%1,753,054CommonSOLE
00773J202SYRESPYRE THERAPEUTICS INC$33.3M1.63%1,988,084CommonSOLE
10919W405DRUGBRIGHT MINDS BIOSCIENCES INC$30.3M1.48%500,000CommonSOLE
045396207ASMBASSEMBLY BIOSCIENCES INC$25.6M1.25%1,000,000CommonSOLE
23284F105CTMXCYTOMX THERAPEUTICS INC$24.5M1.20%7,692,300CommonSOLE
50180M108LBRXLB PHARMACEUTICALS INC$23.7M1.16%1,500,000CommonSOLE
87583X109TNGXTANGO THERAPEUTICS INC$12.6M0.62%1,500,000CommonSOLE
03770N101APGEAPOGEE THERAPEUTICS INC$11.5M0.56%290,000CommonSOLE
713317105PEPGPEPGEN INC$10.9M0.53%2,357,319CommonSOLE
29251M106ENTAENANTA PHARMACEUTICALS INC$9.6M0.47%800,000CommonSOLE
78397T202SABSSAB BIOTHERAPEUTICS INC$8.8M0.43%4,401,500CommonSOLE
45719W205IKTINHIBIKASE THERAPEUTICS INC$8.7M0.43%5,397,488CommonSOLE
G70077105PCSCPERCEPTIVE CAP SOLUTIONS COR$7.9M0.39%750,000CommonSOLE
05338F306AVTXAVALO THERAPEUTICS INC$6.1M0.30%483,000CommonSOLE
92840H400VTGNVISTAGEN THERAPEUTICS INC$5.6M0.27%1,575,000CommonSOLE
G2545C104CBIOCRESCENT BIOPHARMA INC.$5.4M0.26%450,829CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.