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Octagon Capital Advisors LP

Q2 2025 · 13F-HR

Octagon Capital Advisors LPholdings as filed

Filed 2025-08-14 · accession 0001839435-25-000007

$455.6M
Reported value
30
Positions
2025-06-30
Period end
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The Brief · Octagon Capital Advisors LP · Q2 2025

AI · grounded in 13F

Octagon Capital Advisors LP established a new position in DNTH valued at $43.6M. The fund also initiated new stakes in AVBP for $42.4M and VRNA for $31.9M. Additional new positions include TSHA at $29.1M and SPRY at $23.6M. The fund ended the period with 30 positions and total AUM of $455.6M.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
252828108DNTHDIANTHUS THERAPEUTICS INC$43.6M9.57%2,341,667CommonSOLE
04272N102AVBPARRIVENT BIOPHARMA INC$42.4M9.30%1,946,054CommonSOLE
925050106VRNAVERONA PHARMA PLC$31.9M7.00%337,000CommonSOLE
877619106TSHATAYSHA GENE THERAPIES INC$29.1M6.38%12,592,500CommonSOLE
82835W108SPRYARS PHARMACEUTICALS INC$23.6M5.17%1,350,000CommonSOLE
38341P102GOSSGOSSAMER BIO INC$22.6M4.95%18,350,000CommonSOLE
67576A100OCULOCULAR THERAPEUTIX INC$22.5M4.94%2,425,000CommonSOLE
N5749R1002GHMERUS N V$20.5M4.49%389,000CommonSOLE
89532M101TRVITREVI THERAPEUTICS INC$20.1M4.41%3,672,000CommonSOLE
19240Q201COGTCOGENT BIOSCIENCES INC$19.8M4.35%2,763,000CommonSOLE
002120202ATYRATYR PHARMA INC$19.4M4.25%3,820,000CommonSOLE
03753U106APLSUSDAPELLIS PHARMACEUTICALS INC$15.6M3.43%903,500CommonSOLE
67080N101NUVBNUVATION BIO INC$15.0M3.29%7,691,334CommonSOLE
89157D105TRMLTOURMALINE BIO INC$14.5M3.18%905,000CommonSOLE
483497103KALVKALVISTA PHARMACEUTICALS INC$14.4M3.16%1,273,333CommonSOLE
60255C885BRD1EURMIND MEDICINE MINDMED INC$13.8M3.03%2,130,000CommonSOLE
152309100CNTACENTESSA PHARMACEUTICALS PLC$13.5M2.97%1,030,000CommonSOLE
N69605108PHVSPHARVARIS N V$11.8M2.60%672,595CommonSOLE
501575104KYMRKYMERA THERAPEUTICS INC$11.6M2.55%266,000CommonSOLE
00370M103ABVXABIVAX SA$9.7M2.13%1,267,000CommonSOLE
23306J309DBVTDBV TECHNOLOGIES S A$9.3M2.04%1,018,021CommonSOLE
21833P301CRBPCORBUS PHARMACEUTICALS HLDGS$7.7M1.69%1,115,000CommonSOLE
61559X104MLTXMOONLAKE IMMUNOTHERAPEUTICS$7.0M1.53%148,000CommonSOLE
90466Y202UNCYUNICYCIVE THERAPEUTICS INC$4.8M1.05%1,000,000CommonSOLE
64135M105NGNENEUROGENE INC$4.5M0.99%303,000CommonSOLE
G4444H101BBOTHELIX ACQUISITION CORP II$2.7M0.58%250,000CommonSOLE
578784100MAZEMAZE THERAPEUTICS INC$2.2M0.48%177,667CommonSOLE
482929106KLRSKALARIS THERAPEUTICS INC$961,2000.21%360,000CommonSOLE
29479A108ERASERASCA INC$889,0000.20%700,000CommonSOLE
67080N119NUVB/WSNUVATION BIO INC$300,5180.07%154,112CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.