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Casdin Capital, LLC

Q2 2025 · 13F-HR

Casdin Capital, LLCholdings as filed

Filed 2025-08-14 · accession 0000919574-25-004903

$1.10B
Reported value
33
Positions
2025-06-30
Period end
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The Brief · Casdin Capital, LLC · Q2 2025

AI · grounded in 13F

Casdin Capital, LLC established a new position in GENEDX HOLDINGS CORP WGS valued at $323.7M. The fund also initiated new stakes in BIOLIFE SOLUTIONS INC BLFS for $166M and REVOLUTION MEDICINES INC RVMD for $106.2M. Other new additions include STANDARD BIOTOOLS INC LAB and ILLUMINA INC ILMN. Total assets under management stand at $1.1B across 33 positions.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
81663L200WGSGENEDX HOLDINGS CORP$323.7M29.5%3,507,164CommonSOLE
09062W204BLFSBIOLIFE SOLUTIONS INC$166.0M15.1%7,707,165CommonSOLE
76155X100RVMDREVOLUTION MEDICINES INC$106.2M9.68%2,887,933CommonSOLE
34385P108LABSTANDARD BIOTOOLS INC$91.3M8.31%76,075,636CommonSOLE
452327109ILMNILLUMINA INC$61.5M5.60%645,000CommonSOLE
05370A108RNAGBPAVIDITY BIOSCIENCES INC$50.4M4.59%1,775,000CommonSOLE
92539P101VERVE THERAPEUTICS INC$46.0M4.19%4,095,571CommonSOLE
75943R102RLAYRELAY THERAPEUTICS INC$39.4M3.59%11,398,574CommonSOLE
02043Q107ALNYALNYLAM PHARMACEUTICALS INC$26.6M2.42%81,500CommonSOLE
86366E106GPCRSTRUCTURE THERAPEUTICS INC$25.4M2.31%1,225,000CommonSOLE
07373V105BEAMBEAM THERAPEUTICS INC$24.7M2.25%1,450,000CommonSOLE
64135M105NGNENEUROGENE INC$19.4M1.76%1,295,361CommonSOLE
192005106CDXSCODEXIS INC$17.6M1.60%7,200,000CommonSOLE
803607100SRPTSAREPTA THERAPEUTICS INC$16.9M1.54%990,097CommonSOLE
24823R105DNLIDENALI THERAPEUTICS INC$12.5M1.13%890,000CommonSOLE
433000106HIMSHIMS & HERS HEALTH INC$11.5M1.04%230,000CommonSOLE
578784100MAZEMAZE THERAPEUTICS INC$9.3M0.85%758,857CommonSOLE
92337F107VCYTVERACYTE INC$7.5M0.68%276,308CommonSOLE
532457108LLYELI LILLY & CO$6.6M0.60%8,500CommonSOLE
87164F105SNDXSYNDAX PHARMACEUTICALS INC$6.1M0.55%650,000CommonSOLE
81734D104SEPNSEPTERNA INC$5.8M0.53%553,268CommonSOLE
40131M109GHGUARDANT HEALTH INC$5.2M0.47%100,000CommonSOLE
30063P105EXKEXACT SCIENCES CORP$4.8M0.44%90,000CommonSOLE
74168J101PRMEPRIME MEDICINE INC$3.9M0.35%1,567,175CommonSOLE
00847X104AGIOAGIOS PHARMACEUTICALS INC$3.3M0.30%100,000CommonSOLE
00091E109ABSIABSCI CORPORATION$2.5M0.23%973,260CommonSOLE
69404D108PACBPACIFIC BIOSCIENCES CALIF IN$897,4710.08%723,767CommonSOLE
75629V104RXRXRECURSION PHARMACEUTICALS IN$836,5340.08%165,323CommonSOLE
15673T100IPSCCENTURY THERAPEUTICS INC$686,1900.06%1,228,190CommonSOLE
21217B100CTNMCONTINEUM THERAPEUTICS INC$588,8820.05%148,333CommonSOLE
37611X209DNAGINKGO BIOWORKS HOLDINGS INC$410,5460.04%36,493CommonSOLE
61225M102GLUEMONTE ROSA THERAPEUTICS INC$387,9230.04%86,014CommonSOLE
87990A106TNYATENAYA THERAPEUTICS INC$221,2350.02%361,969CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.