Q1 2026 · 13F-HR
Exome Asset Management LLCholdings as filed
Filed 2026-05-15 · accession 0001420506-26-001033
$193.3M
Reported value
56
Positions
2026-03-31
Period end
The Brief · Exome Asset Management LLC · Q1 2026
AI · grounded in 13F
Exome Asset Management LLC closed its position in WVE for a reduction of $7.17M. The fund established new positions in XBI for $7.66M, INSM for $4.36M, and MLTX for $4.01M. Other notable exits included closing positions in AZNN and JAZZ.
Holdings as filed
| CUSIP | Ticker | Issuer | Value | % port. | Shares | Class | Voting |
|---|---|---|---|---|---|---|---|
| 74006W207 | PRAX | PRAXIS PRECISION MEDICINES I | $14.6M | 7.58% | 45,469 | Common | SOLE |
| 19240Q201 | COGT | COGENT BIOSCIENCES INC | $10.7M | 5.54% | 278,533 | Common | SOLE |
| 29337E102 | ELVN | ENLIVEN THERAPEUTICS INC | $8.6M | 4.46% | 220,091 | Common | SOLE |
| 462222100 | IONS | IONIS PHARMACEUTICALS INC | $8.3M | 4.27% | 110,064 | Common | SOLE |
| 78464A870 | XBI | SPDR SERIES TRUST | $7.7M | 3.96% | 60,000 | PUT | SOLE |
| 40131M109 | GH | GUARDANT HEALTH INC | $7.6M | 3.95% | 82,736 | Common | SOLE |
| 23282W605 | CYTK | CYTOKINETICS INC | $6.8M | 3.54% | 103,718 | Common | SOLE |
| 532457108 | LLY | ELI LILLY & CO | $6.4M | 3.34% | 7,012 | Common | SOLE |
| 022307102 | ALMS | ALUMIS INC | $6.2M | 3.18% | 279,176 | Common | SOLE |
| 10806X102 | BBIO | BRIDGEBIO PHARMA INC | $5.0M | 2.59% | 67,492 | Common | SOLE |
| 92337R101 | VERA | VERA THERAPEUTICS INC | $4.6M | 2.39% | 114,991 | Common | SOLE |
| 457669307 | INSM | INSMED INC | $4.4M | 2.25% | 26,651 | Common | SOLE |
| 036752103 | ELV | ELEVANCE HEALTH INC FORMERLY | $4.3M | 2.22% | 14,677 | Common | SOLE |
| 00847X104 | AGIO | AGIOS PHARMACEUTICALS INC | $4.2M | 2.19% | 125,060 | Common | SOLE |
| 91307C102 | UTHR | UNITED THERAPEUTICS CORP DEL | $4.2M | 2.16% | 7,053 | Common | SOLE |
| 61559X104 | MLTX | MOONLAKE IMMUNOTHERAPEUTICS | $4.0M | 2.08% | 215,376 | Common | SOLE |
| 23282W955 | CYTK | CYTOKINETICS INC | $4.0M | 2.05% | 60,000 | PUT | SOLE |
| 632307104 | NTRA | NATERA INC | $3.7M | 1.93% | 18,650 | Common | SOLE |
| 76243J105 | RYTM | RHYTHM PHARMACEUTICALS INC | $3.5M | 1.83% | 40,581 | Common | SOLE |
| 91324P102 | UNH | UNITEDHEALTH GROUP INC | $3.5M | 1.80% | 12,862 | Common | SOLE |
| 03753U106 | APLSUSD | APELLIS PHARMACEUTICALS INC | $3.4M | 1.78% | 85,517 | Common | SOLE |
| 92337C203 | VSTM | VERASTEM INC | $3.4M | 1.75% | 636,700 | Common | SOLE |
| 88025U109 | TXG | 10X GENOMICS INC | $3.3M | 1.69% | 154,194 | Common | SOLE |
| 101137107 | BSX | BOSTON SCIENTIFIC CORP | $3.0M | 1.57% | 48,347 | Common | SOLE |
| G01767105 | ALKS | ALKERMES PLC | $3.0M | 1.54% | 84,103 | Common | SOLE |
| 07725L902 | ONC | BEONE MEDICINES LTD | $3.0M | 1.54% | 10,000 | CALL | SOLE |
| 61225M102 | GLUE | MONTE ROSA THERAPEUTICS INC | $3.0M | 1.53% | 179,484 | Common | SOLE |
| 46120E602 | ISRG | INTUITIVE SURGICAL INC | $2.9M | 1.52% | 6,358 | Common | SOLE |
| 005329107 | ADAG | ADAGENE INC | $2.9M | 1.49% | 736,845 | Common | SOLE |
| 04280A100 | ARWR | ARROWHEAD PHARMACEUTICALS IN | $2.9M | 1.48% | 45,721 | Common | SOLE |
| G2545C104 | CBIO | CRESCENT BIOPHARMA INC. | $2.8M | 1.46% | 153,191 | Common | SOLE |
| 75943R102 | RLAY | RELAY THERAPEUTICS INC | $2.8M | 1.43% | 278,302 | Common | SOLE |
| 578784100 | MAZE | MAZE THERAPEUTICS INC | $2.6M | 1.37% | 88,510 | Common | SOLE |
| 23284F105 | CTMX | CYTOMX THERAPEUTICS INC. | $2.5M | 1.27% | 521,468 | Common | SOLE |
| 05338F306 | AVTX | AVALO THERAPEUTICS INC | $2.4M | 1.23% | 159,341 | Common | SOLE |
| 022307952 | ALMS | ALUMIS INC | $2.3M | 1.20% | 105,000 | PUT | SOLE |
| 377322102 | GKOS | GLAUKOS CORP | $2.2M | 1.16% | 20,874 | Common | SOLE |
| 21833P301 | CRBP | CORBUS PHARMACEUTICALS HLDGS | $2.2M | 1.14% | 234,136 | Common | SOLE |
| 70975L107 | PEN | PENUMBRA INC | $2.1M | 1.07% | 6,300 | Common | SOLE |
| 834203309 | SLNO | SOLENO THERAPEUTICS INC | $2.1M | 1.07% | 61,673 | Common | SOLE |
| 53635D202 | LQDA | LIQUIDIA CORPORATION | $1.7M | 0.89% | 45,796 | Common | SOLE |
| 98937L105 | ZBIO | ZENAS BIOPHARMA INC | $1.6M | 0.82% | 80,730 | Common | SOLE |
| 53635D952 | LQDA | LIQUIDIA CORPORATION | $1.5M | 0.78% | 40,000 | PUT | SOLE |
| 44975P103 | NBP | NOVABRIDGE BIOSCIENCES | $1.4M | 0.73% | 576,960 | Common | SOLE |
| 152309950 | CNTA | CENTESSA PHARMACEUTICALS PLC | $1.4M | 0.71% | 34,700 | PUT | SOLE |
| 45166A902 | IDYA | IDEAYA BIOSCIENCES INC | $1.3M | 0.69% | 40,000 | PUT | SOLE |
| 45166A902 | IDYA | IDEAYA BIOSCIENCES INC | $1.3M | 0.69% | 40,000 | CALL | SOLE |
| 35104E100 | FDMT | 4D MOLECULAR THERAPEUTICS IN | $1.2M | 0.63% | 130,564 | Common | SOLE |
| 65343E207 | NXTC | NEXTCURE INC | $1.2M | 0.63% | 115,500 | Common | SOLE |
| 696389402 | PALI | PALISADE BIO INC | $1.1M | 0.54% | 600,000 | Common | SOLE |
| G31249108 | ESTA | ESTABLISHMENT LABS HLDGS INC | $743,818 | 0.38% | 13,100 | Common | SOLE |
| 89422G957 | TVTX | TRAVERE THERAPEUTICS INC | $594,200 | 0.31% | 20,000 | PUT | SOLE |
| 53630X203 | LPCN | LIPOCINE INC NEW | $486,279 | 0.25% | 60,861 | Common | SOLE |
| 03879J100 | ABUS | ARBUTUS BIOPHARMA CORP | $339,678 | 0.18% | 75,484 | Common | SOLE |
| Y95308955 | WVE | WAVE LIFE SCIENCES LTD | $217,500 | 0.11% | 30,000 | PUT | SOLE |
| 20454B904 | CMPX | COMPASS THERAPEUTICS INC | $132,779 | 0.07% | 25,100 | CALL | SOLE |
Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.