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Catalio Capital Management, LP

Q4 2025 · 13F-HR

Catalio Capital Management, LPholdings as filed

Filed 2026-02-17 · accession 0001958125-26-000002

$565.8M
Reported value
45
Positions
2025-12-31
Period end
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The Brief · Catalio Capital Management, LP · Q4 2025

AI · grounded in 13F

Catalio Capital Management, LP exited its position in ABBV for a reduction of $35.85M. The fund also closed its position in BBIO for $32.34M and trimmed its holdings in ISRG by 61.86%. To offset these exits, the fund established new positions in GILD for $35.51M and BMY for $34.95M.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
375558103GILDGILEAD SCIENCES INC$35.5M6.28%289,312CommonSOLE
110122108BMYBRISTOL-MYERS SQUIBB CO$34.9M6.18%647,899CommonSOLE
101137107BSXBOSTON SCIENTIFIC CORP$34.4M6.07%360,428CommonSOLE
107924102BBOTBRIDGEBIO ONCOLOGY THERAPEUT$31.4M5.55%410,700CommonSOLE
532457108LLYELI LILLY & CO$27.9M4.92%25,923CommonSOLE
252828108DNTHDIANTHUS THERAPEUTICS INC$26.9M4.76%653,572CommonSOLE
04351P101ASNDUSDASCENDIS PHARMA A/S$25.4M4.49%119,265CommonSOLE
87164F105SNDXSYNDAX PHARMACEUTICALS INC$25.1M4.44%1,196,807CommonSOLE
478160104JNJJOHNSON & JOHNSON$25.0M4.42%120,840CommonSOLE
75886F107REGNREGENERON PHARMACEUTICALS$23.0M4.07%29,797CommonSOLE
86366E106GPCRSTRUCTURE THERAPEUTICS INC$17.6M3.11%252,901CommonSOLE
834203309SLNOSOLENO THERAPEUTICS INC$16.7M2.95%360,340CommonSOLE
23282W605CYTKCYTOKINETICS INC$16.4M2.90%258,381CommonSOLE
28176E108EWEDWARDS LIFESCIENCES CORP$15.9M2.82%187,048CommonSOLE
46120E602ISRGINTUITIVE SURGICAL INC$15.4M2.72%27,209CommonSOLE
632307104NTRANATERA INC$14.3M2.52%62,273CommonSOLE
00650F109ADPTADAPTIVE BIOTECHNOLOGIES COR$13.3M2.36%821,195CommonSOLE
00370M103ABVXABIVAX SA$13.3M2.35%98,514CommonSOLE
868459108SUPNSUPERNUS PHARMACEUTICALS INC$12.8M2.26%257,465CommonSOLE
35168W103GUTSFRACTYL HEALTH INC$12.1M2.14%5,491,866CommonSOLE
603170101MLYSMINERALYS THERAPEUTICS INC$12.0M2.13%331,849CommonSOLE
71722W107PHATPHATHOM PHARMACEUTICALS INC$11.6M2.05%698,996CommonSOLE
000899104ADMAADMA BIOLOGICS INC$10.3M1.82%564,461CommonSOLE
03940C100ACLXGBXARCELLX INC$10.2M1.80%156,109CommonSOLE
26818M108DYNDYNE THERAPEUTICS INC$10.2M1.80%519,715CommonSOLE
254604101IRONDISC MEDICINE INC$8.8M1.55%110,427CommonSOLE
67576A100OCULOCULAR THERAPEUTIX INC$8.7M1.53%714,501CommonSOLE
81734D104SEPNSEPTERNA INC$8.2M1.45%294,360CommonSOLE
74365U107TARAPROTARA THERAPEUTICS INC$7.7M1.36%1,446,254CommonSOLE
N90064101QUREUNIQURE NV$6.9M1.22%288,345CommonSOLE
68062P106OLMAOLEMA PHARMACEUTICALS INC$6.7M1.18%267,058CommonSOLE
880881107430TERNS PHARMACEUTICALS INC$5.5M0.98%136,958CommonSOLE
90400D108RAREULTRAGENYX PHARMACEUTICAL IN$3.7M0.66%162,550CommonSOLE
42238D107HTFLHEARTFLOW INC$3.3M0.59%113,857CommonSOLE
384747101GRALGRAIL INC$2.6M0.46%30,313CommonSOLE
359616109FULCFULCRUM THERAPEUTICS INC$2.3M0.40%201,301CommonSOLE
090168105BLLNBILLIONTOONE INC$2.1M0.37%25,505CommonSOLE
28617K101ELDNELEDON PHARMACEUTICALS INC$1.9M0.34%1,259,820CommonSOLE
44916K106HYPRHYPERFINE INC$1.3M0.23%1,320,041CommonSOLE
697947109PVLAPALVELLA THERAPEUTICS INC NE$1.1M0.19%10,452CommonSOLE
48576U205KPTIKARYOPHARM THERAPEUTICS INC$1.1M0.19%142,984CommonSOLE
59102M104MGXMETAGENOMI INC$856,9690.15%528,993CommonSOLE
N0731H103ATAIATAI BECKLEY NV$805,1490.14%196,858CommonSOLE
690145206OMOUTSET MED INC$438,8150.08%118,279CommonSOLE
81728A207SNSESENSEI BIOTHERAPEUTICS INC$157,0410.03%14,718CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.